Primary immunodeficiencies (PIDs) are a group of over 300 different conditions that affect how the body’s immune system works. People affected by PIDs have elements of their immune systems missing or not working. It causes frequent severe infections in children and adults, both viral and bacterial, which are difficult to treat despite the use of various treatments, such as targeted antibiotic therapy. Primary immunodeficiencies can also manifest as autoimmune diseases when the body is attacked by its own immune system. These diseases also include neurological conditions such as PANDAS or autoimmune encephalitis.
Immunoglobulins are natural constituents of the human body.
Human immunoglobulin used in immunotherapy contains mainly immunoglobulin G (IgG – 95%) with a broad spectrum of activity against infectious agents. It contains immunoglobulin G subclasses closely proportional to those in human plasma.
Adequate doses of this medicine may restore abnormally low immunoglobulin G levels to normal. Human immunoglobulin is fully bioavailable in the body’s circulation system immediately after intravenous administration.
The half-life of human immunoglobulin is approximately 40 days. It can vary from patient to patient, especially for those with primary immunodeficiency.
Immunoglobulin therapy is mainly used in the following cases:
- TREATMENT OF PRIMARY IMMUNODEFICIENCIES.
- TREATMENT OF PRIMARY IMMUNODEFICIENCY WITH THE USE OF HUMAN IMMUNOGLOBULIN GIVEN WITH RECOMBINATED HUMAN HYALURONIDASE.
- TREATMENT WITH IMMUNOGLOBULIN TRANSFUSION IN NEUROLOGICAL DISEASES, INCLUDING PANDAS.
Therapy at the St. Luke’s Medical Center: how does it work?
- Contact us by e-mail: firstname.lastname@example.org, we will provide all the necessary information and arrange a qualifying appointment.
- The Patient’s qualification for therapy takes place during a medical visit. The doctor informs the patient about the course of the treatment process and about all necessary tests and premedication, and also calculates the dose of the medication.
- After completing all formalities, appropriate medication is ordered in a dose individually selected for the needs of a given Patient. The waiting time is up to 3 weeks. The date of administration of the medication is arranged at the same time.
- The administration of immunoglobulins lasts from 1 to 3 days and is carried out using a special infusion pump with constant monitoring of the patient’s vital signs and medical supervision. The procedure may take 4 to 8 hours. During this time, the Patient stays in an office equipped with a comfortable sofa, a place to eat meals and prepare hot drinks.
- The drug is administered on an outpatient basis. During the whole process, the Patient is under the care of nursing staff and a doctor who can be contacted in case of urgent needs and in situations requiring medical intervention.
- We provide assistance in organizing accommodation for the duration of therapy.